Current Studies

Flu Vaccine Study

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Participants needed: Infants: 6-23 months

Do you want to protect your child against the flu?

About influenza (flu)

  • Influenza or ‘flu’ is a highly contagious infection that is caused by a virus (germ) and spread by nasal droplets.
  • Symptoms include sudden high fever, headache, chills, muscle ache and cough.
  • The flu can also lead to other serious diseases such as pneumonia (an infection of the lungs), which can be dangerous in young children
  • The flu virus changes a little bit each year so a new vaccine is required each fall to protect against new “strains” year.

What is the purpose of this study?

  • Vaccination with a flu vaccine is the best way to prevent influenza and avoid complications and is recommended by public health.
  • Children under two years of age may not have strong immune responses to regular flu vaccines
  • The vaccine being studied is called FLUAD™ Pediatric (aTIV). It is referred to as aTIV.  It contains three strains of inactivated (killed) flu virus so is referred to as a “trivalent” influenza vaccine, and the “a” refers to an “adjuvant” named MF59. It is an inactivated vaccine (not live).  An adjuvant is a substance used to increase the body’s immune response.
  • The other vaccine included in this study is called Fluzone. It is a “quadrivalent” influenza vaccine (QIV).  This vaccine contains four components (four killed strains) of the flu virus and is developed for the protection against flu in persons six-months of age and older. It is an inactivated vaccine (not live). It does not contain an adjuvant.
  • The purpose of this study is to determine if giving the adjuvanted vaccine to children who have not had a flu vaccine, before will improve their immune responses to annual flu vaccines.

Is my child eligible to participate?

  • We are in need of infants between the ages of 6-23 months, who have not received the flu vaccine.

Participant commitment

  • The study involves a total of seven visits to the IWK Health Centre over an 18-month period.
  • These visits will include a physical exam, vaccination, blood tests, and questions about your child’s health.
  • The total time commitment is approximately 3-5 hours.

You will receive:

  • Parents will receive $50/visit and a parking pass for the IWK Health Centre.

Contact Cathy Brown

Phone (902) 470-7015


Find out more about this study

Please fill out the form below and we will be in touch shortly.