Participants needed: 40-80 years old.
About Chronic Obstructive Pulmonary Disease (COPD)
- Chronic Obstructive Pulmonary Disease (COPD) is a lung disease that makes it hard to breathe. One of the problems of COPD is that your lungs can be prone to infections. These infections can cause episodes of worsening symptoms, called acute exacerbation of COPD (AECOPD).
- Acute exacerbations (worsening of symptoms) are not only unpleasant; they may also make it more difficult for you to breathe, even after the infection is gone.
- The worsening of symptoms is often due to infection caused by two bacteria – Haemophilus influenzae(NTHi) and Moraxella catarrhalis (Mcat).
What is the purpose of this study?
- There are no vaccines on the market to protect against NTHi and/or Mcat.
- In the current study, the NTHi/Mcat vaccine will be given for the first time to people with COPD.
- The purpose of the study is to see if the vaccine can help reduce the number of times you experience episodes of worsening symptoms(exacerbation) and to further collect information on the safety of the vaccine. Information will also be collected to see whether the vaccine may be able to protect against infections with NTHi and Mcat.
Am I eligible to participate?
- We are in need of study volunteers between the ages of 40-80 years old.
- Participants in this study will receive either the study vaccine or a placebo (an injection consisting of salt water that will not affect you).
- At least nine scheduled visits over approx. 15 months
- Study visits may include blood sampling, EKG, physical exam, CXR, collection of health information
- Subjects receive two study vaccines – at day 1 and day 60
You will receive:
- There will be no costs to you to take part in this study.
- Study participants will be reimbursed compensated for each study visit, and a parking pass will be provided for parking at the IWK Health Centre
Contact Cathy Brown